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This issue was addressed by improving the assay with β-phycoerythrin as the fluorescent probe

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An 8-week trial that tested different NR doses (100, 300, and 1000 mg) in overweight but healthy adults found: No serious problems Nobody experienced flushing Side effects were similar between placebo and NR groups5 Liposomal NAD+ products don't have as much clinical data as precursors like NR or NMN